570 Protein Structure, Function, and Stability II: Aggregation & Disease


Description:
We invite submissions pertaining to protein structure, function, stability, and dynamics. Studies that utilize experimental and/or computational approaches are welcome. Topics include, but are not limited to, structural or functional analysis, engineering of new proteins by structure-based design, effects of post-translational modifications, and analysis of protein conformational stability.

Sponsor:
Bioengineering


Chair:
Robert Luo
Manager
GSK
DPD
King of Prussia, PA
Phone Number: 610-270-7787
Email: robert.g.luo@gsk.com

Co-chairs:
Seongkyu Yoon
Assistant Professor
University of Massachusetts Lowell
Chemical Engineering
11 University Avenue, Lowell, US
Lowell, MA
Email: Seongkyu_Yoon@uml.edu

Han Li
Assistant Professor
University of California, Irvine
Chemical Engineering and Materials Science
Irvine, CA
Email: hanl5@uci.edu


Papers:
570a
Engineering a Self-Assembling Peptide System Derived from Beta-Amyloid
Jason Candreva, New York University; Edward Chau, New York University; Jin Ryoun Kim, New York University
570b
Competition between Ligands: How Retinol-Binding Protein and Beta-Amyloid Compete for Binding to Transthyretin
Parth Mangrolia, University of Wisconsin-Madison; Chandler Est, University of Wisconsin-Madison; Regina M. Murphy, University of Wisconsin-Madison
570c
Understanding the Role of Glycine in Amyloid Protein Aggregation through Rationally Designed Protein Sequences
S. Zeb Vance, University of South Carolina; Rachel Hall, University of South Carolina; Jamie Crawford, University of South Carolina; Gram L. Booth, University of Arkansas; Christa N. Hestekin, University of Arkansas; Melissa A. Moss, University of South Carolina
570d
N-Terminal Hypothesis for Alzheimer’s Disease: Analyzing Dimers of a β peptide and its Protective and Causative Mutants
Bhanushee Sharma, Rensselaer Polytechnic Institute; Srivathsan V. Ranganathan, The RNA Institute, University at Albany, State University of New York; Mirco Sorci, Rensselaer Polytechnic Institute; Christopher Lennon, University at Albany, State University of New York; James Van Deventer, Tufts University; Annalisa Scimemi, University at Albany, State University of New York; Georges Belfort, Rensselaer Polytechnic Institute
570e
Computational Modeling of Amyloid Aggregation Kinetics to Gain Insights into the Effect of Ions on Amyloid Aggregation
Aditi Sharma, Georgia Institute of Technology; Harrison B. Rose, Georgia Institute of Technology; Yury O. Chernoff, Georgia Institute of Technology; Sven H. Behrens, Georgia Institute of Technology; Andreas S. Bommarius, Georgia Institute of Technology
570f
Human Islet Amyloid Polypeptide: Identifying Early-Stage Aggregation Mechanisms through Molecular Simulation
Ashley Guo, University of Chicago; Juan J. de Pablo, University of Chicago
570g
The Role of Cholesterol in Membrane Protein Activity
Anne S. Robinson, University of Delaware
Abstract Submissions Closed
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
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