504 Protein Engineering I: Therapeutics


Description:
This session will focus on engineering polypeptides for therapeutic applications. Topics of interest include, but are not limited to, selective cell targeting, imaging, and disruption of biological processes that contribute to disease.

Sponsor:
Bioengineering


Chair:
Benjamin J. Hackel
Assistant Professor
University of Minnesota
Chemical Engineering and Materials Science
421 Washington Avenue SE
Minneapolis, MN
55455
Email: hackel@umn.edu

Co-Chair:
James Van Deventer
Assistant Professor
Tufts University
Chemical and Biological Engineering
Medford, MA
Phone Number: 6176276339
Email: James.Van_Deventer@tufts.edu


Papers:
504a
Engineering and Profiling the Substrate Specificity of Human Proteases for Therapeutic Applications
Carl A. Denard, University of Texas Austin; Rasha Yaghi, University of Texas at Austin; Brent L. Iverson, Univ. of Texas
504b
A Novel Transthyretin Peptide Mimic As a Therapeutic for Alzheimer’s Disease
Kayla Pate, University of Wisconsin-Madison; Regina M. Murphy, University of Wisconsin-Madison
504c
Directing Reversible Cell-Cell Interactions with Evolved Fibronectin Domains
Clifford M. Csizmar, University of Minnesota; Lawrence A. Stern, University of Minnesota; Jacob R. Petersburg, University of Minnesota; Benjamin J. Hackel, University of Minnesota; Carston R. Wagner, University of Minnesota
191ci
Design of a Cholesterol-Binding Peptide to Inhibit Bacterial Toxin Activity
Evan Koufos, Lehigh University; Angela C. Brown, Lehigh University
504e
Enhancing the Chemical Versatility of Yeast Display to Target the Tumor Microenvironment
Jessica T. Stieglitz, Tufts University; Haixing P. Kehoe, Tufts University; Gregory I. Berumen, Tufts University; Hanan Z. Lane, Tufts University; Laura B. Quinto, Tufts University; James Van Deventer, Tufts University
504f
Tunable Thermal Bioswitches for in vivo Control of Biological Therapeutics
Dan Piraner, California Institute of Technology; Mohamad Abedi, California Institute of Technology; Brittany Moser, California Institute of Technology; Audrey Lee-Gosselin, California Institute of Technology; Mikhail G. Shapiro, California Institute of Technology
504g
Now You See Me, Now You Don’T—Building Better Biologics through Immune Evasion
Karl E. Griswold, Dartmouth College
Abstract Submissions Closed
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
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