643 Advances in Metabolic Engineering I: Emerging Tools and Techniques


Description:
Metabolic engineering is the targeted improvement of the cellular metabolic phenotype using recombinant DNA technology. This session emphasizes pathway-level engineering. Approaches are typically mostly experimental and are focused on a specific pathway and metabolites rather than metabolism as a whole. Example areas include: strategies to enhance the production of natural products, pathway engineering for the production of novel products, and the application of evolutionary techniques for improving production of a metabolite. Abstracts describing new developments in these topics are sought, and the session is open to papers focused on any type of organism, microbial consortium, or cell-free system.

Sponsor:
Bioengineering


Chair:
Thomas J. Mansell
Iowa State University
Iowa State University
Chemical and Biological Engineering
Ames, IA
Phone Number: 515-294-7177
Email: mansell@iastate.edu

Co-Chair:
Nikhil U. Nair
Assistant Professor
Tufts University
Chemical & Biological Engineering
4 Coby St, STC 276
Medford, MA
02155
Email: nikhil.nair@tufts.edu


Papers:
Improving Glucaric Acid Production By Alleviating Oxidative Stress in E. coli
Lisa M. Guay, Massachusetts Institute of Technology; Kristala L. J. Prather, Massachusetts Institute of Technology
Investigation of Metabolite Channeling in Central Bacterial Pathways
Mary Abernathy, Washington University in St. Louis; Lian He, Washington University in St. Louis; Whitney D. Hollinshead, Washington University in St. Louis; Yinjie Tang, Washington University in St. Louis
Cell-Free Metabolic Engineering for Heterologous in vivo Pathway Optimization
Joseph Rollin, National Renewable Energy Laboratory; Christopher Johnson, National Renewable Energy Laboratory; Peter St. John, National Renewable Energy Laboratory; Gregg T. Beckham, National Renewable Energy Laboratory
Genetically Programmable Assembly of Microbial Communities for Enhanced Biosynthetic Efficiency
Bradley Silverman, California Institute of Technology; Mark Kozlowski, California Institute of Technology; David Tirrell, California Institute of Technology
A Generic Strategy to Maintain Stable, Multi-Member Microbial Consortia
NaRae Lee, National University of Singapore; Jeremy Jie Ming Kwok, National University of Singapore; Xiaoqiang Ma, National University of Singapore; Liming Yang, National University of Singapore; Kang Zhou, National University of Singapore; Dong-Yup Lee, National University of Singapore
Abstract Submissions Closed
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division