362 In silico Systems Biology II: Health Applications


Description:
Computational approaches are needed to unravel the complexity of biological networks and understand how they function as a system. This session will focus on recent advances in the application of in silico methods and/or the development of novel computational techniques to understand biological systems.

Sponsor:
Bioengineering
Co-Sponsor(s):
Engineering Fundamentals in Life Science (15D)


Chair:
Rajib Saha
Assistant Professor
University of Nebraska-Lincoln
Department of Chemical and Biomolecular Engineering
213 Othmer Hall
Lincoln, NE
68508
Email: rsaha2@unl.edu

Co-chairs:
Mark P. Brynildsen
Assistant Professor
Princeton University
Chemical and Biological Engineering
25 William Street
Princeton, NJ
08540
Email: mbrynild@princeton.edu

Jason E. Shoemaker
University of Pittsburgh
Department of Computational and Systems Biology
Pittsburgh, PA
Email: jason.shoemaker@pitt.edu


Papers:
362a
Causal Network Modeling of Calcium Wave Propagation in Rat Liver Lobules
Aalap Verma, Daniel Baugh Institute for Functional Genomics and Computational Biology; Anil Antony, Thomas Jefferson University; Hirenkumar Makadia, Thomas Jefferson University; Jan Hoek, Thomas Jefferson University; Babatunde A. Ogunnaike, University of Delaware; Rajanikanth Vadigepalli, Thomas Jefferson University
362b
Characterizing Host Immune Cell and Local Transcriptional Dynamics during Influenza Infection
Muying Wang, University of Pittsburgh; Satoshi Fukuyama, University of Tokyo; Yoshihiro Kawaoka, University of Wisconsin-Madison; Jason E. Shoemaker, University of Pittsburgh
362c
A Two-State Model-Based Cell Clustering and Network Inference for Single-Cell Gene Expression Data
Nan Papili Gao, ETH Zurich; Thomas Hartmann, ETH; Rudiyanto Gunawan, ETH Zurich
362d
Maximum Entropy Approach for Parameter Estimation in Signaling Networks
Purushottam Dixit, Columbia University; Eugenia Lyashenko, Columbia University; Mario Niepel, Harvard University; Dennis Vitkup, Columbia University
362e
Computation-Driven Mechanistic Understanding of the Cellular Cost and Regulation of Melanin Production
Wheaton Schroeder, University of Nebraska - Lincoln; Jyothi Kumar, University of Nebraska - Lincoln; Rajib Saha, University of Nebraska-Lincoln; Steve Harris, University of Nebraska - Lincoln
362f
Metabolic Modeling of Interactions Between Pseudomonas aeruginosa and Staphylococcus aureus in Cystic Fibrosis Biofilm Infections
Poonam Phalak, University of Massachusetts Amherst; Michael A. Henson, University of Massachusetts - Amherst; George O'Toole, Geisel School of Medicine at Dartmouth
362g
Hybrid Models Explain Emergent Dynamics in Complex Cell Populations
Neda Bagheri, Northwestern University
Abstract Submissions Closed
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
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