524543 The Quaternary State of Polymerized Human Hemoglobin Regulates Oxygenation of Breast Cancer Solid Tumors: A Theoretical and Experimental Study

Donald Belcher1, Julia Ju2, Jin Hyen Baek3, Ayla Yalamanoglu3, Paul Buehler3, Daniele Gilkes2,4 and Andre Palmer1, (1)Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH, (2)Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, MD, (3)Division of Blood Components and Devices, FDA/CBER, Silver Spring, MD, (4)Department of Oncology, The Johns Hopkins University, Baltimore, MD