662 Engineering in Cancer Biology and Therapy I: Signaling


Description:
This session will cover a broad spectrum of approaches engineers have developed to understand and treat cancer. Abstracts could include include studies on fundamental biological processes involved in the development of cancer and in diagnosis or therapy of cancer. Experimental systems and computational approaches can range from microorganisms to mammalian cells to multi-cellular organisms (Drosophila and worms) and animal models, with a focus on the intersection between engineering and cancer.

Sponsor:
Engineering Fundamentals in Life Science
Co-Sponsor(s):
Biomaterials (08B)


Chair:
Samira M. Azarin
University of Minnesota
Chemical Engineering and Materials Science
Minneapolis, MN
Email: azarin@umn.edu

Co-Chair:
Roger Harrison
Professor
University of Oklahoma
Chemical, Biological and Materials Engineering
100 E. Boyd St.
Norman, OK
73019
Phone Number: 405-325-4367
Fax Number: 405-325-5813
Email: rharrison@ou.edu


Papers:
Activation of IRE1α Protein By Palmitate through the Transmembrane Domain and Its Implications in Progression of Cancer
Amrita Oak, Michigan State University; Christina Chan, Michigan State Uiversity
Probing the Role of Cancer Lipid Microenvironment in the Regulation of Notch Cleavage By Gamma-Secretase
Lane Gilchrist, City College of New York of CUNY; William Houlihan, City College of New York (Graduate Center, CUNY); Marilia Barros, Sloan Kettering Institute (MSKCC); Yueming Li, Memorial Sloan-Kettering Cancer Center
The Quaternary State of Polymerized Human Hemoglobin Regulates Oxygenation of Breast Cancer Solid Tumors: A Theoretical and Experimental Study
Donald Belcher, The Ohio State University; Julia Ju, The Johns Hopkins University; Jin Hyen Baek, FDA/CBER; Ayla Yalamanoglu, FDA/CBER; Paul Buehler, FDA/CBER; Daniele Gilkes, The Johns Hopkins University; Andre Palmer, The Ohio State University
Pharmacometabonomics Approach for Early Prediction of Chemotherapy Induced Peripheral Neuropathy
Parul Verma, Purdue University; Jamie Renbarger, Indiana University School of Medicine; Jodi Skiles, Indiana University School of Medicine; Bruce Cooper, Purdue University; Doraiswami Ramkrishna, Purdue University
Single-Cell Tumor Metabolism of Immune Checkpoint Inhibitors Determines Optimal Dosing for This Class of Antibody Therapeutics
Ian Nessler, University of Michigan; Cornelius Cilliers, University of Michigan; Greg Thurber, University of Michigan
Abstract Submissions Closed
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division