Niki Loverdou1, Gabriella Nilsson Hall2, Kristel Bernaerts3, Bart Ghesquière4, Geert Carmeliet5, Ioannis Papantoniou2 and Liesbet Geris6, (1)Department of Development and Regeneration, KULeuven, Prometheus, Division of Skeletal Tissue Engineering, Leuven, Belgium, (2)Skeletal Biology and Engineering Research Center, KULeuven, Leuven, Belgium, (3)Bio- and Chemical Systems Technology, Reactor Engineering, and Safety (CREaS), Department of Chemical Engineering, KU Leuven, University of Leuven, Leuven, Belgium, (4)Department of Oncology,KULeuven, Metabolomics Core Facility VIB Center for Cancer Biology KULeuven, Leuven, Belgium, (5)Department of Development and Regeneration, KULeuven, Division of Skeletal Tissue Engineering, Leuven, Belgium, (6)Department of Mechanical Engineering, KULeuven, Biomechanics section, Leuven, Belgium