Session: Poster Session: Engineering Fundamentals in Life Science (2018 AIChE Annual Meeting)

190e

Preservation of Therapeutic Potential of Culture Expanded Human Mesenchymal Stem Cells By Preventing a Breakdown of Cellular Homeostasis
Xuegang Yuan, Florida State University; Yijun Liu, Florida State University; Ang-Chen Tsai, Florida State University; Teng Ma, Florida State University

190f

Induction of Definitive Endoderm from Human Pluripotent Stem (hPS) Cells
Saber Meamardoost, University at Buffalo, State University of New York at Buffalo; Natesh Parashurama, University at Buffalo, State University of New York

190g

Peptoid-Based Coatings for Differentiation of Human Embryonic Stem Cells into Neural Cells
Jesse Roberts, University of Arkansas; German Perez, University of Arkansas; Safiya Belbina, University of Arkansas; Michael Borrelli, University of Arkansas for Medical Sciences; Ruben M. Ceballos, University of Arkansas; Shannon L. Servoss, University of Arkansas

190h

Biomolecular Rate Indicators of Human Mesenchymal Stem Cell Chondrogenesis
Yi Zhong, Case Western Reserve University; Sruthi Sivakumar, Case Western Reserve University; Arnold I. Caplan, Case Western Reserve University; Jean F. Welter, Case Western Reserve University; Harihara Baskaran, Case Western Reserve University

190i

Three-Dimensional Finite Element Modeling of Dynamic BMP Gradient Formation in Zebrafish Embryonic Development
Linlin Li, Purdue University; Xu Wang, Purdue University; Adrian Buganza Tepole, Purdue University; David M. Umulis, Purdue University

190j

Cell Population Balance of Cardiovascular Spheroids Derived from Human Induced Pluripotent Stem Cells
Julie Bejoy, FAMU-FSU College of Engineering; Yuanwei Yan, Florida State University; Junfei Xia, Florida State University; Jingjiao Guan, Florida State University; Yan Li, Florida State University

190k

Understanding the Role of Central Carbon Metabolism in Myeloid and Monocytic Hematopoietic Differentiation Programs in Patient Derived HL-60 Cells
David Dai, Cornell University; Andrew Yen, Cornell University; Jeffrey Varner, Cornell University

190l

Reverse-Engineering Calcium Signaling in a Developing Organ
Jeremiah J. Zartman, University of Notre Dame

190m

NANOG Restores the Myogenic Differentiation Potential of Senescent Myoblasts
Aref Shahini, University at Buffalo, The State University of New York; Debanik Choudhury, University at Buffalo; Kalyan Vydiam, University at Buffalo; Nika Rajabian, University at Buffalo; Thy Nguyen, University at Buffalo; Pedro Lei, University at Buffalo; Stelios T. Andreadis, University at Buffalo

190n

Transport of Amyloid-β across the Blood Brain Barrier By P-Glycoprotein: A Novel Therapeutic Target in Alzheimer’s Disease
Hope Holt, University of South Carolina; Elizabeth Moore, University of South Carolina; Madeline Riese, University of South Carolina; Michelle Faucett, University of South Carolina; Francisco González, University of South Carolina; Melissa A. Moss, University of South Carolina

190o

In Situ Growth of Acetylcholinesterase-Oxime Polymer Conjugate Scavengers of Organophosphate Nerve Agent Toxicity
Libin Zhang, Carnegie Mellon University; Nicholas Harris, Carnegie Mellon University; Weihang Ji, Carnegie Mellon University; Hironobu Murata, Carnegie Mellon University; Krzysztof Matyjaszewski, Carnegie Mellon University; Alan Russell, Carnegie Mellon University

190p

Ultrasound Triggered Synergistic Thrombolysis Using Tpa Loaded Microbubbles for the Treatment of Acute Ischemic Stroke
Vishnu Sunil, National University of Singapore; Vijay Kumar Sharma, National University Hospital; Chi-Hwa Wang, National University of Singapore

190q

Synergism of EGCG and Curcumin Co-Modified on Hyaluronic Acid on Inhibiting β-Amyloid Aggregation and Cytotoxicity
Zhiqiang Jiang, Tianjin University; Xiaoyan Dong, Tianjin University; Yan Sun, Tianjin University

190r

Inherent Variability in Inflammatory Response to Shunts in the Treatment of Hydrocephalus
Carolyn Harris, Wayne State University; Prashant Hariharan, Wayne State University; Marc Del Bigio, University of Manitoba; David Limbrick, Washington University in St. Louis; James P McAllister, Washington University in St. Louis

190s

Polydopamine Nanoparticles: A Possible Strategy to Fight Against Cancer
Celia Nieto, University of Salamanca; Milena Vega, University of Salamanca; Gema Marcelo, University of Salamanca; Miguel A. Galán, University of Salamanca; Eva Martín del Valle, University of Salamanca

190t

GGL: A Natural Pharmaceutical Molecule for the Treatment of Breast Cancer
Muhammad Raisul Abedin, Missouri University of Science and Technology; Sutapa Barua, Missouri University of Science and Technology

190u

Encapsulation of 6-Thioguanine on Al-MOF Basolite A100 and Its Controlled Delivery
Cole Grinnell, Morgan State University; Adetunji Adeniran-Adetoye, Morgan State University; Rena Lapidus, University of Maryland School of Medicine; Alexander Samokhvalov, Morgan State University

190v

Rheological Response of Chromatin to DNA Damage
Daniel Whitefield, Carnegie Mellon University; Kris Noel Dahl, Carnegie Mellon University; Li Lan, University of Pittsburgh - Hillman Cancer Center; Shelly Peyton, University of Massachusetts

190x

Implantable Humanized Pre-Metastatic Niches Capture Microenvironmental Regulation of Disseminated Human Tumor Cells
Ryan Carpenter, University of Massachusetts; Jun-Goo Kwak, University of Massachusetts Amherst; Jungwoo Lee, University of Massachusetts-Amherst

190y

Increased Resistance Enhances Cell Motility
Kaustav Bera, Johns Hopkins University; Adrianna Boen, Johns Hopkins University; Panagiotis Mistriotis, Johns Hopkins University; Konstantinos Konstantopoulos, Johns Hopkins University

190z

Effects of Immune Modulation on Melanoma Progression
Adeyinka Lesi, City College of New York; Richard White, Memorial Sloan Kettering Cancer Center; David S. Rumschitzki, The City College of The City University of New York

190aa

Exploring the Metabolic Shift Associated with Cancer Hypermutation
Jonathan L. Robinson, Chalmers University of Technology; Raphael Ferreira, Chalmers University of Technology; Francesco Gatto, Chalmers University of Technology; Jens Nielsen, Chalmers University of Technology

190ab

Engineering Cancer Cells for Cancer Research
Everardo Gonzalez Gonzalez, EverDo S.A. de C.V., Calle Sexta 816, Col. La herradura, CP. 67140, Guadalupe; Aimé A. Cuéllar Monterrubio, Departamento de Mecatrónica y Eléctrica, Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias; Grissel Trujillo-de Santiago, Centro de Biotecnología-FEMSA, Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias; Mario Moisés Alvarez, Centro de Biotecnología-FEMSA, Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias

190ac

Label-Free Interference-Based Single-Cell Phenotyping of Highly Metastatic Cancer Cells in Liquid Biopsy Applications
Jose C. Contreras-Naranjo, Texas A&M University; Arul Jayaraman, Texas A&M University; Victor M. Ugaz, Texas A&M University

190ad

Biodegradable Multilayered Nanofilms for Isolation and Recovery of Circulating Tumor Cells
Wei Li, Texas Tech University; Ziye Dong, Texas Tech University; Dan Yu, Texas Tech University

190ae

Mesenchymal Stem Cell Infiltration and Remodeling of Microfiber/Hydrogel Composites for Ligament Tissue Engineering
Hagar Kenawy, Virginia Tech; Aaron S. Goldstein, Virginia Tech; Dina Gadalla, 6786963773; Patrick Thayer, Cellink AB

190af

Simulating Bacterial Infection to Trick Neutrophils into Enhancing Vaccine-Induced Immune Response
Seth Boese, Texas Tech University

190ag

Antitumor and Antioxidant Activities of Crude Proteins Extracts from Enzymatically Treated Microalgae
Sulaiman Al-Zuhair, UAE University; Sinan Battah, Essex University

190ah

Quantitative Cellular and Tissue Pharmacokinetics of Protein-Drug Conjugates in Solid Tumors for Designing Effective Clinical Therapies
Eshita Khera, University of Michigan; Cornelius Cilliers, University of Michigan; Ian Nessler, University of Michigan; Sumit Bhatnagar, University of Michigan; Greg Thurber, University of Michigan

190ai

Engineering Peptide Targeting Liposomal Drug Delivery to Improve Selectivity for HER2-Overexpressing Breast Cancer
Baksun Kim, University of Notre Dame; Jaeho Shin, University of Notre Dame; Junmin Wu, Department of Chemistry and Biochemistry; Laurie Littlepage, Department of Chemistry and Biochemistry; Basar Bilgicer, University of Notre Dame

190aj

High-Temporal-Resolution Measurements of Polymer Micellization Kinetics By Integrating a Microfluidic Device with Synchrotron X-Ray
Joseph Kalkowski, University of Illinois at Chicago; Chang Liu, University of Illinois at Chicago; Paola Leon Plata, University of Illinois at Chicago; Magdalena Szymusiak, University of Illinois at Chicago; Pin Zhang, University of Illinois at Chicago

190ak

Spatial-Temporal Dynamics of the Biofilm Formation
Liliana Angeles-Martinez, Swiss Federal Institute of Technology (EPFL); Vassily Hatzimanikatis, Swiss Federal Institute of Technology (EPFL)

190al

Not Always Resistant: Antibiotic Susceptibility of Bacterial Cells Changes during Early Stage Biofilm Formation
Huan Gu, Syracuse University; Zhaowei Jiang, Syracuse University; Dacheng Ren, Syracuse Biomaterials Institute

190am

Modulation of Ultrasensitive Signaling in Bacteria By Mechanical Forces
Jyot Antani, Texas A&M University; Pushkar Lele, Texas A&M University

190an

Impact of Red Blood Cell Rigidity on the Vascular Wall Adhesion of Vascular-Targeted Carriers: Implications for Performance in Diseased Blood Flow
Mario Gutierrez, University of Michigan; Omolola Eniola-Adefeso, University of Michigan

190ao

Hyper-Activation of Cellular Rigidity Sensing By Solid Surface Tension of Biomaterials and Silicone Breast Implants
Zhu Cheng, Cornell University; Chung-Yuen Hui, Cornell University; Matthew Paszek, Cornell University

190aq

Dynamics and Mechanics of Rotational Collective Cell Movements
Abraham E. Wolf, Princeton University; Celeste M. Nelson, Princeton University

190ar

Modeling the Extensibility and Strain-Hardening Inelasticity of Fibrin Fibers during Coagulation
Megan Cala, University of Pittsburgh; Joseph J. McCarthy, University of Pittsburgh; Robert S. Parker, University of Pittsburgh

190as

Biophysical Model of CsrA-mRNA Interactions Expands Canonical Understanding of the CsrA Global Regulator Protein
Abigail N. Leistra, The University of Texas at Austin; Grant Gelderman, The University of Texas at Austin; Steven Sowa, The University of Texas at Austin; Alex Moon-walker, The University of Texas at Austin; Howard M. Salis, Pennsylvania State University; Lydia M. Contreras, The University of Texas at Austin

190at

Detection of Truncation on RNA By RARE
Wen-Jie Zhuang, Ming Chi University of Technology; Chung-Yu Wu, Ming Chi University of Technology; Chao-Lin Liu, Ming Chi University of Technology

190au

Exploring Tumor Metabolic Heterogeneity through Integration of Single Cell RNA-Seq Analysis and Genome-Scale Metabolic Models
Daniel Cook, Chalmers University of Technology; Jonathan L. Robinson, Chalmers University of Technology; Jens Nielsen, Chalmers University of Technology

190av

Using Metabolomics As a High-Sensitivity Quality Control Tool for the Characterization of Chondrogenic Microtissues
Niki Loverdou, Prometheus, Division of Skeletal Tissue Engineering; Gabriella Nilsson Hall, KULeuven; Kristel Bernaerts, KU Leuven, University of Leuven; Bart Ghesquière, Metabolomics Core Facility VIB Center for Cancer Biology KULeuven; Geert Carmeliet, Division of Skeletal Tissue Engineering; Ioannis Papantoniou, KULeuven; Liesbet Geris, Biomechanics section

190aw

Identifying an Individual’s Comprehensive Epitope Repertoire
Sumaiya Islam, Auburn University; Robert Pantazes, Auburn University

190ax

Integrated Epigenome and Transcriptome Sequencing from the Same Cell
Siddharth S. Dey, University of California, Santa Barbara

190ay

CRISPR-Based Editing Reveals Edge-Specific Effects in Biological Networks
Chance Nowak, The University of Texas at Dallas

190az

Raps: Rapid Annotation of Photosynthetic Systems
Alexander Metcalf, Colorado School of Mines; Nanette R. Boyle, Colorado School of Mines

190ba

High-Throughput Screening of Alkaline Phosphatase Activity in Single Algal Cells Shows Heterogeneity Under Deviant Phosphorus Conditions
Manibarathi Vaithiyanathan, Louisiana State University; Jacob Pettigrew, Louisiana State University; Travis Dugas, Louisiana State University; Yusef Kana, Louisiana State University; Ann Nguyen, St. Joseph's Academy; Adam Melvin, Louisiana State University

190bb

Effect of Glycosylation on the Aggregation of Insulin Fragments
Paul Praveen Nakka, Missouri University of Science and Technology; Daniel Forciniti, Missouri University of Science and Technology

190bc

Synergistic Anti-Oxidation Effect of Resveratrol at Lipid Membrane Surface
Jin Han, Osaka University; Keishi Suga, Osaka University; Keita Hayashi, Nara National College of Technology; Yukihiro Okamoto, Osaka University; Hiroshi Umakoshi, Osaka University

190bd

Sucrose Concentration Determines Giant Unilamellar Vesicle Size during Electroformation
Bridget Black, Rowan University; Erica Spatafore, Rowan University; Gary Thompson, Rowan University

190be

Supported Biomembrane Microenvironments Characterized at the Micro- and Nanoscale for Gamma-Secretase Functional Analysis and Assays
Lane Gilchrist, City College of New York of CUNY; William Houlihan, City College of New York (Graduate Center, CUNY); Marilia Barros, Sloan Kettering Institute (MSKCC); Eitan Wong, Sloan Kettering Institute (MSKCC),; Yueming Li, Memorial Sloan-Kettering Cancer Center

190bf

Endocytosis and Trafficking of siRNA-Containing Complexes
Daniel Vocelle, Michigan State University; Olivia Chesniak, Michigan State University; Chauncey Splichal, Michigan State University; Milton Smith, Michigan State University; Christina Chan, Michigan State University; S. Patrick Walton, Michigan State University

190bg

Electrospun Microfibers and Lipid-Based Nanoparticles: A Combination Delivery System for Resveratrol and siRNA
Thikrayat Al-Attar, Oklahoma State University; Sundararajan Madihally, oklahoma state university

190bh

Procaine Loading and Release from MIL-100 (Cr,Fe) and MIL-101(Cr,Fe), and Pectine-MOF Matrice
Mehran Aliari Miavaghi, Istanbul Technical University; Banu Kocaaga, Istanbul Technical University; Ahmet Sirkecioglu, Istanbul Technical University

190bi

Multiscale Structural Characterization of Epithelial Cell Monolayers Associated with the Addition of Permeability Enhancers for Enhancing Drug Delivery
Shiyuan Zheng, Carnegie Mellon University; Katherine Fein, Carnegie Mellon University; Nicholas G. Lamson, Carnegie Mellon University; Kris Noel Dahl, Carnegie Mellon University; Kirill Lavrenyuk, Carnegie Mellon University; Kathryn Whitehead, Carnegie Mellon University

190bj

Biophysical, Cytotoxicity and Cellular Uptake Studies of Novel Amphiphilic Fluorophores for Photodynamic Therapy (PDT)
Poornima Kalyanram, Rochester Institute of Technology; Istvan Stadler, Rochester General Hospital; Anju Gupta, Rochester Institute of Technology

190bk

Suprachoroidal Space Injection of in-Situ Forming Bevacizumab-Hyaluronic Acid Hydrogel Using a Microneedle to Increase Drug Retention Time
Jae Hwan Jung, Georgia Institute of Technology; Seongshik Kim, Georgia Institute of Technology; Mark R. Prausnitz, Georgia Institute of Technology

190bm

A Systems Engineering Framework for Diagnosis and Treatment of Chronic Obstructive Pulmonary Diseases (COPD)
Navid Ghadipasha, University of Delaware; Anais Chalant, Air Liquide company; Bin Yu, Air Liquide company; Babatunde A. Ogunnaike, University of Delaware

190bn

Network Motif Properties Influence Transmission of Autosomal Allelic Imbalance to Phenotype Relevant Signals
Shibin Mathew, Harvard Medical School; Alexander Gimelbrant, Harvard Medical School; Suzanne Gaudet, Harvard Medical School

190bo

Genetic Engineering for the Production of Curcumin in Human Cells
Logan Warriner, University of Kentucky; Daniel W. Pack, University of Kentucky

190bp

Proteins Covalently Conjugated to Phenylpiperazine-Containing Polymers Experience Selectively Enhanced Intestinal Epithelial Transport
Katherine Fein, Carnegie Mellon University; Chad Cummings, Carnegie Mellon University; Hironobu Murata, Carnegie Mellon University; Rebecca Ball, Carnegie Mellon University; Alan Russell, Carnegie Mellon University; Kathryn A. Whitehead, Carnegie Mellon University

190bq

Spatial and Temporal Imaging Reveals Single-Cell Heterogeneity during Virus Growth and Infection Spread
Huicheng Shi, University of Wisconsin-Madison; John Yin, University of Wisconsin - Madison

190br

Blood Rheology across Species: Differences and Similarities
Jeffrey S. Horner, University of Delaware; Antony N. Beris, University of Delaware; Norman J. Wagner, University of Delaware; Donna S. Woulfe, University of Delaware

190bs

Addressing Complexity of Health Impact Assessment in Industrially Contaminated Sites Via the Exposome Paradigm
Dimosthenis Sarigiannis, Aristotle University of Thessaloniki; Spyros Karakitsios, Aristotle University of Thessaloniki

190a

A Hidden Light – Selection of Green Fluorescent Protein That Evades an Existing Antibody Response
Jacob Furlon, Dartmouth College; Karl E. Griswold, Dartmouth College

190b

Continuous Protease Assays Using Liquid Crystal As a Reporter
Mahbuba Jannat, National University of Singapore

190c

Novel Library Design and Selection Methods for Identifying Drug-like Antibodies
Alec Desai, University of Michigan; Lilia Rabia, Rensselaer Polytechnic Institute; Yulei Zhang, University of Michigan; Mark Julian, Rensselaer Polytechnic Institute; Seth Ludwig, Rensselaer Polytechnic Institute; Kathryn Tiller, Rensselaer Polytechnic Institute; Peter Tessier, University of Michigan

190d

Study of the Magnetic Properties of Glioblastoma Cancer Stem-like Cells and Non-Stem Tumor Cells Using Magnetophoresis for Label-Less Separation
James Kim, Ohio State University; Jeffrey J. Chalmers, The Ohio State University

190 Poster Session: Engineering Fundamentals in Life Science