466 Mixing Scale-up/Scale-down Issues in Pharmaceutical and Biopharmaceuticals Processes


Description:
Mixing Issues and Scale-up/Scale-Down Strategies for the Production of Pharmaceutical and Biopharmaceuticals

Sponsor:
North American Mixing Forum
Co-Sponsor(s):
Pharmaceutical Discovery, Development and Manufacturing Forum (26), Pharmaceuticals (15B), Pilot Plants (12B)


Chair:
Piero Armenante
Distinguished Professor
New Jersey Institute of Technology
Otto H. York Department of Chemical and Materials Engineering
Tiernan Hall, Suite 150, Newark College of Engineering, New Jersey Institute of Technology
Newark, NJ
07102-1982
Email: piero.armenante@njit.edu

Co-Chair:
Joerg Theuerkauf
The Dow Chemical Co.
Fluid Mechanics and Mixing, Engineering Sciences, Core R&D
Midland, MI
48674
Email: jtheuerkauf@dow.com


Papers:
466a
Hydrodynamics Characteristics of a Stirred Tank Provided with Angle-Mounted Impellers Using Computational and Experimental Approaches
Chadakarn Sirasitthichoke, New Jersey Institute of Technology; Ji Ma, New Jersey Institute of Technology; Piero M. Armenante, New Jersey Institute of Technology
466b
Experimental and CFD Study of Mixing Two Fluids of Different Properties and Its Application in Biological Drug Product Manufacture
Weixian Shi, Bristol-Myers Squibb; Wei Chen, Bristol-Myers Squibb; Rushikesh Patel, BMS; Christoph Bernoulli, BMS; Jasmine M. Rowe, Bristol-Myers Squibb; Melissa Bentley, BMS; Nobel Vale, Bristol-Myers Squibb Company; Dimuthu A. Jayawickrama, Bristol-Myers Squibb Company
466c
Recirculation Mixing and Heat Transfer Characteristics for Continuous Slug-Flow Cooling Crystallization
Jingcai Cheng, Institute of Process Engineering, Chinese Academy of Sciences; Yan Zhang, Institute of Process Engineering, Chinese Academy of Sciences; Chao Yang, University of Chinese Academy of Sciences; Mo Jiang, Virginia Commonwealth University; Zai-Sha Mao, Institute of Process Engineering, Chinese Academy of Sciences
466d
Mini Continuous Stirred Tank Reactors (mini-CSTR) for Cell and Tissue Culture Applications
Salvador Gallegos Martínez, Centro de Biotecnología-FEMSA, Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias; Christian Carlos Mendoza Buenrostro, Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias; Pamela I. Rellstab-Sanchez, Centro de Biotecnología-FEMSA, Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias; Ricardo Hernández Medina, Centro de Biotecnología-FEMSA, Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias; Ingrid Anaya Morales, Centro de Biotecnología-FEMSA, Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias; Mohamadmahdi Samandari, College of Engineering, University of Tehran; Everardo Gonzalez Gonzalez, Centro de Biotecnología-FEMSA, Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias; Andrés García Rubio, Centro de Biotecnología-FEMSA, Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias; Ciro Angel Rodríguez-González, Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias; Grissel Trujillo-de Santiago, Centro de Biotecnología-FEMSA, Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias; Mario M. Alvarez, Centro de Biotecnología-FEMSA, Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias
466e
Power Dissipation and Power Numbers for a Retreat-Blade Impeller in Pharmaceutical Mixing Tanks and Reactors Using an Experimentally Validated Computational Approach
Adam J. Bindas, New Jersey Institute of Technology; Chadakarn Sirasitthichoke, New Jersey Institute of Technology; Piero M. Armenante, New Jersey Institute of Technology
Abstract Submissions Closed
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