634 Rational and Computational Techniques for Protein Engineering


Description:
This session will focus on computational and rational design approaches to protein engineering including, but not limited to, (1) advances in rational protein engineering, (2) advances in computational protein engineering, and (3) hybrid computational and experimental techniques for improved protein engineering approaches. Submissions combining computationally/rationally inspired designs with experimental screening are especially encouraged.

Sponsor:
Bioengineering


Chair:
Seok Hoon Hong
Illinois Institute of Technology
Chemical and Biological Engineering
2145 Sheridan Rd.
Chicago, IL
60208
Phone Number: 3125678950
Fax Number: 3125678950
Email: shong26@iit.edu

Co-Chair:
Tim Whitehead
Assistant Professor
Michigan State University
Chemical Engineering and Materials Science
2527 Engineering Building
East Lansing, MI
48824
Email: taw@egr.msu.edu


Papers:
Rational Design of Glucose-Responsive Insulin Using Pharmacokinetic Modeling
Naveed Bakh, Massachusetts Institute of Technology; Gili Bisker, Massachusetts Institute of Technology; Michael A. Lee, Massachusetts Institute of Technology; Xun Gong, Massachusetts Institute of Technology; Abel B. Cortinas, Massachusetts Institute of Technology; Robert Langer, Massachusetts Institute of Technology; Daniel A. Anderson, Massachusetts Institute of Technology; Zhen Gu, University of North Carolina School of Medicine; Sanjoy Dutta, JDRF; Michael Weiss, Case Western Reserve University; Michael Strano, Massachusetts Institute of Technology
Computational Design of High-Resolution Protein Crystals
Jeliazko R. Jeliazkov, Johns Hopkins University; Aaron Robinson, Johns Hopkins University; James M. Berger, Johns Hopkins Medical Institute; Bertrand E. Garcia-Moreno, Johns Hopkins University; Jeffrey J. Gray, Johns Hopkins University
A Novel Approach for the Computational De Novo Design of Antibody Structures and Alternative Scaffolds
Varun Chauhan, Auburn University; Robert Pantazes, Auburn University
Engineering the Active Site Microenvironment of a Thermostable Alcohol Dehydrogenase As a Means to Modulate Kinetic Activity
Walaa Abdallah, Columbia University; Louis Lancaster, UC Riverside; Ian Wheeldon, UC Riverside; Scott Banta, Columbia University
Transition Path Methods for Understanding Catalysis By Proteins
Natasha Seelam, Massachusetts Institute of Technology; Bruce Tidor, Massachusetts Institute of Technology
Invited Speaker - TBA
Eric Althoff, Arzeda
Abstract Submissions Closed
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division