W292
An Improved Horse Reference Genome for Enhanced Biological Discovery

Date: Sunday, January 10, 2016
Time: 8:00 AM
Room: Royal Palm Salon 5-6
Richard Green , University of California, Santa Cruz, Santa Cruz, CA
Horses are one of the most intensely studied domesticated animals. In the 5,500 years since domestication, humans have performed selective breading to produce a variety of horse breads with dramatically different phenotypic traits. Thus, horses are a useful model system for understanding the selective forces underlying domestication and the genetic architecture of specific morphological and behavioral traits. However, the horse genome - a necessary reagent for gene-mapping studies - is not as well assembled as most genetic model organisms.
We used a new method for high-contiguity long-range genome assembly to produce a new, de novo reference horse genome assembly. We will discuss the technology behind this assembly and demonstrate the accuracy and increased utility of this genome for revealing the recent population history of horses.